Cancer to Fibroblasts: Fibrosarcoma


Fibrosarcoma is a rare type of cancer that affects cells known as fibroblasts. Fibroblasts are responsible for creating the fibrous tissue found throughout the body. Tendons, which connect muscles to bones, are made up of fibrous tissue.

When fibrosarcoma strikes, the body's fibroblasts lose control and multiply excessively. This either creates fibrous tissue where it is not supposed to be or in excess quantities. Like other cancers, fibrosarcoma can spread throughout the body.

Fibrosarcoma is part of a wider family of cancers known as sarcomas. Other examples include osteosarcoma, which specifically affects bone, and rhabdomyosarcoma, which specifically affects muscle.

Rarely, fibrosarcoma can occur in bone, but it usually affects the nearby fibrous tissue, not the bone itself.

According to Macmillan Cancer Support, the symptoms of soft tissue sarcomas, such as fibrosarcoma, take a long time to appear. When they do appear, symptoms can include:

  • painless or painful swelling in various parts of the body, and especially the limbs
  • a cough or breathlessness
  • dark stool
  • vomiting blood
  • irregular bleeding from the vagina
  • pain in the abdomen

Fibrosarcoma affecting bones can be even trickier to identify by symptoms alone. According to Macmillan Cancer Support, symptoms of primary bone cancer include:

  • persistent pain in the area of the tumor, which might feel like a sprain or "growing pains"
  • swelling around the bone, which often does not show up until the tumor is quite large
  • difficulty moving a joint or limb
  • numbness in areas of the body, due to the tumor pressing on nerves
  • fragile, easily broken bones, as the bone has been weakened by cancer


The Journal of Orthopedic Oncology offers information in all aspects of primary, malignant tumors. Osteosarcoma, Ewing's sarcoma, chondrosarcoma, chordoma, and soft tissue sarcomas etc it also deals with diagnostic methods, therapeutic approaches, clinical, laboratory research and reconstructive techniques.

The Journal includes a wide range of fields in its discipline to create a platform for the authors to make their contribution towards the journal and the editorial office promises a peer review process for the submitted manuscripts for the quality of publishing.


The Journal is using Editorial Manager System for quality in review process. Editorial Manager is an online manuscript submission, review and tracking systems. Review processing is performed by the editorial board members of Orthopedics & oncology or outside experts; at least two independent reviewer’s approval followed by editor approval is required for acceptance of any citable manuscript. Authors may submit manuscripts and track their progress through the system.

The Journal Considers Research article, Review articles, editorial, letter, case reports, short communications, original articles from leading scientists and scholars around the world in all areas of related to Malignantosteoid, Multilobular tumour of bone, Chondrosarcoma, Chordoma, Osteosarcoma, Ewing's sarcomaetc., which come under the scope of the journal.

You may submit your manuscript as an e-mail attachment to the Editorial Office at

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Coordinator| Journal of Orthopedic Oncology

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